Despite their utility, these medications can be abused by some persons with severe mental illness who require neuroleptics. Survey research has found that many abusers of antiparkinsonians used these medications “to get high, to increase pleasure, to decrease depression, to increase energy and to relax” (Buhrich et al. 2000, p. 929). The survey also found that the misuse of other drugs accompanied the misuse of antiparkinsonian medications. Consequently, in the context of co-occurring mental health and substance use disorders, providers and consumers need to be aware of and openly communicate about the abuse potential of these medications.